RSM logo
JRSM

Home Current issue Browse archive Alerts About the journal Feedback
 
J R Soc Med 1985;78:47-55
© 1985 Royal Society of Medicine

This Article
Right arrow Send a Quick Comment
Right arrow Alert me when this article is cited
Right arrow Alert me when Quick Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brookes, G. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Journal of the Royal Society of Medicine, Vol 78, Issue 1 47-55, Copyright © 1985 by Royal Society of Medicine

ORIGINAL ARTICLES

Immune complex-associated deafness: preliminary communication

GB Brookes

During the last year patients presenting with progressive bilateral or sudden sensorineural deafness of unknown aetiology have been investigated for possible abnormal immune activity. Twenty-six cases are reported in which significantly raised circulating immune complexes were present, together with 2 cases of clinical autoimmune deafness where the complexes were normal. Thirty-six control subjects were also studied. Following a review of the clinical features, the pathogenesis of this new association with sensorineural deafness is discussed. In some cases the aetiology is probably autoimmune, and in others related to infection. In certain patients the deafness has been partly reversed by medical treatment with systemic steroids or plasma exchange. It is hypothesized that circulating immune complexes may reflect a previously unrecognized final common pathophysiological pathway in a variety of cochleovestibular disorders.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Arch Otolaryngol Head Neck SurgHome page
J. M. Heaton and R. P. Mills
Sensorineural Hearing Loss Associated With Birdshot Retinochoroidopathy
Arch Otolaryngol Head Neck Surg, June 1, 1993; 119(6): 680 - 681.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
G. B. Brookes
Circulating Immune Complexes in Meniere's Disease
Arch Otolaryngol Head Neck Surg, May 1, 1986; 112(5): 536 - 540.
[Abstract] [PDF]


Get Through Series

 Secrets of Success series Recent Advances in Gastroenterology 11