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J R Soc Med 1985;78:826-829
© 1985 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 78, Issue 10 826-829, Copyright © 1985 by Royal Society of Medicine

ORIGINAL ARTICLES

Recombinant human gamma-interferon in primary hepatocellular carcinoma

A Forbes, PJ Johnson and R Williams

A phase II trial of recombinant human gamma-interferon in the treatment of unresectable primary hepatocellular carcinoma is reported. The trial was terminated prematurely after recruitment of only 7 patients because of unacceptable toxicity, predominantly renal. There was no evidence of response in any of the 7 patients but some evidence that disease progression was more rapid during the treatment period.
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A. M. DI BISCEGLIE, V. K. RUSTGI, J. H. HOOFNAGLE, G. M. DUSHEIKO, and M. T. LOTZE
Hepatocellular Carcinoma
Ann Intern Med, March 1, 1988; 108(3): 390 - 401.
[Abstract] [PDF]


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