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J R Soc Med 1985;78:838-841
© 1985 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 78, Issue 10 838-841, Copyright © 1985 by Royal Society of Medicine

ORIGINAL ARTICLES

Iron status in hypogammaglobulinaemia

HI Atrah

Iron, transferrin and ferritin were measured in serum samples from 16 patients with primary hypogammaglobulinaemia. Transferrin saturation was low in 12 patients (75%) and serum ferritin was low in 9 patients (56.25%). Both parameters were low, confirming the state of iron deficiency, in 6 patients (37.5%). These figures are highly significant (P less than 0.01) when compared with the prevalence of iron deficiency in the general population. Eight patients were maintained on intravenous immunoglobulin infusions and the rest on intramuscular immunoglobulin injections, their mean serum IgG being 4.4 g/l and 2.6 g/l respectively. There was no difference in the prevalence of iron deficiency between the two groups.
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