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J R Soc Med 1986;79:25-29
© 1986 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 79, Issue 1 25-29, Copyright © 1986 by Royal Society of Medicine


ORIGINAL ARTICLES

Optic nerve hypoplasia in infancy

AR Fielder, MI Levene, JQ Trounce and MS Tanner

Certain features of optic nerve hypoplasia (ONH), its systemic associations and investigation are exclusive to infancy. These include the facility to use cranial ultrasound, difficulties in assessing ocular features and visual function, and neonatal hypoglycaemia and jaundice. Six infants with ONH are presented; cerebral abnormalities were demonstrated by cranial ultrasound in five. Neonatal cholestatic jaundice and hypoglycaemia occurred in one infant. Two died and represent a group likely to remain undetected unless routine ophthalmic examination of neurologically abnormal neonates is undertaken. In infancy, both ocular and systemic aspects of ONH can be investigated simply and without sedation.
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