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J R Soc Med 1986;79:462-464
© 1986 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 79, Issue 8 462-464, Copyright © 1986 by Royal Society of Medicine

ORIGINAL ARTICLES

Carcinoma of the colon--association with low dietary vitamin A in females: preliminary communication

GH Tomkin, L Scott, C Ogbuah and M O'Shaughnessy

Seventeen patients with non-metastatic carcinoma of the colon (9 male, 8 female) were compared with age- and sex-matched controls in a study examining the relationship of diet and altered cholesterol metabolism with carcinoma of the colon. Bile acid excretion in the faeces was significantly less in cancer patients (P less than 0.001), and a significantly lower intake of retinol (P less than 0.01) and vitamin A (P less than 0.05) was demonstrated in female cancer patients. There was no difference between patients and controls in hepatic cholesterol enzyme activity or in fasting plasma lipid levels.
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