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J R Soc Med 1989;82:595-597
© 1989 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 82, Issue 10 595-597, Copyright © 1989 by Royal Society of Medicine

ORIGINAL ARTICLES

Use of auditory evoked responses as a measure of recovery from benzodiazepine sedation

KR Milligan, J Lumsden, RC Howard, JP Howe and JW Dundee
Department of Anaesthetics, Queen's University, Belfast.

The amplitude of the P300 component of auditory evoked responses was found to be depressed by benzodiazepine sedation and was subsequently used to monitor the recovery of volunteers sedated with midazolam. The amplitude of the evoked responses was found to be highly correlated with blood midazolam levels but to be no more sensitive than standard psychomotor testing in assessing recovery from sedation.
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This article has been cited by other articles:


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B.R.P. Birch and R. A. Miller
An assessment of resedation following flumazenil-induced antagonism of intravenous midazolam: comparison of psychomotor and amnesic recovery with a non-sedated reference group
J Psychopharmacol, January 1, 1995; 9(2): 103 - 111.
[Abstract] [PDF]


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