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J R Soc Med 1989;82:91-92
© 1989 Royal Society of Medicine

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Journal of the Royal Society of Medicine, Vol 82, Issue 2 91-92, Copyright © 1989 by Royal Society of Medicine

ORIGINAL ARTICLES

Plasma and lipoprotein lipids and apolipoproteins AI, AII and B in patients with chronic airflow limitation

CH Bolton, E Mulloy, J Harvey, LG Downs and M Hartog
University Department of Medicine, Bristol Royal Infirmary.

Plasma and lipoprotein cholesterol and triglycerides, and plasma apolipoproteins AI, AII and B were compared in patients with chronic airflow limitation, and normal controls matched for body mass index. The controls were non-smokers, and free from respiratory disease. High-density lipoprotein (HDL) cholesterol concentration was significantly elevated in the patients, due mainly to a raised HDL2 cholesterol level. HDL triglyceride was significantly lower in the patients. All other lipids were not different from normal. Apolipoprotein AI levels were significantly raised in the patients but other apolipoproteins were unchanged. The changes found may account in part for the fact that patients with chronic airflow limitation have a lower incidence of atherosclerotic heart disease.
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