Journal of the Royal Society of Medicine, Vol 84, Issue 3 140-143, Copyright © 1991 by Royal Society of Medicine

ORIGINAL ARTICLES

Non-secretory adenomas of the pituitary treated by trans-ethmoidal sellotomy

GR Shone, SH Richards, MD Hourihan, R Hall, JP Thomas and MF Scanlon
Department of Otolaryngology, University Hospital of Wales, Heath Park, Cardiff.

A consecutive series of 35 clinically non-secretory pituitary adenomas treated surgically by the transethmodial approach is presented. Mean age at presentation was 60 years, with a male-to-female ratio of 2:1. These tumours present later than hormone secreting tumours: 90% were over 2 cm in diameter at operation. Seventy-one per cent of patients had impaired vision and 89% had hypopituitarism. Surgical treatment relieved or significantly improved visual fields in 79% of patients with impaired vision. Ninety-one per cent required permanent hormone replacement. Mean follow-up was for 4.4 years. Five tumours recurred, causing recurrent visual symptoms. No tumours recurred in those patients treated with postoperative radiotherapy, but follow-up in this group was only for a mean of 2.7 years.
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