JRSM > Volume 94, Number 5 > Pp. 221-225

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The renal tubular acidoses

Robert J Unwin PhD FRCP     Giovambattista Capasso MD  ¹

Centre for Nephrology, Royal Free and University College Medical School, University College London, UK
¹ Department of Nephrology, Second University of Naples, Italy

View larger version (20K): [in a new window]   Figure 1. Main sites of H+ secretion

 

View larger version (17K): [in a new window]   Figure 2. Current cellular models of tubule acidification (proximal versus distal). CA=carbonic anhydrase; PC=principal cell; -IC=intercalated cell; p.d.=potential difference

 

View larger version (17K): [in a new window]   Figure 3. Acid-base renal tubular cell membrane transporters

 

View larger version (16K): [in a new window]   Figure 4. Urine pH versus plasma bicarbonate in renal tubular acidosis (RTA) (adapted from Refs 19 and 31)

 

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