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J R Soc Med 2002;95:227-230
doi:10.1258/jrsm.95.5.227
© 2002 Royal Society of Medicine

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The hypocretin/orexin system

I O Ebrahim MRCPsych   R S Howard MD FRCP  1 M D Kopelman PhD FRCPsych   M K Sharief MD  1   A J Williams FRCP  2

Department of Psychiatry, Lane Fox Unit, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK
1 Department of Neurology, Lane Fox Unit, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK
2 Sleep Disorders Centre, Lane Fox Unit, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK



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Figure 1. Projections of the hypocretin (orexin) system (A), to cholinergic neurons, reticular formation and spinal cord; (B), to thalamus and basal ganglia; (C), to basal forebrain; (D), to amygdala and dopaminergic neurons including suprachiasmatic nucleus; (E), to locus coeruleus.

 

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The Cholesterol Controversy